GHRP-2 — Vendor Pricing & Purity Guide
Research Overview
GHRP-2 (Growth Hormone Releasing Peptide-2, also known as Pralmorelin) is a synthetic hexapeptide that stimulates growth hormone secretion through the ghrelin/GHS-R1a receptor. Developed as an improvement over GHRP-6, it produces stronger GH release per unit dose while generating less appetite stimulation. GHRP-2 is approved in Japan under the brand name GHRP Kaken as a diagnostic agent for GH deficiency.
GHRP-2 is considered the most potent GH secretagogue among the classical GHRPs, producing the highest peak GH levels. However, this potency comes with more off-target effects than Ipamorelin — GHRP-2 can elevate cortisol and prolactin at standard research doses, though less dramatically than GHRP-6. It occupies a middle position in the GHRP selectivity spectrum: less selective than Ipamorelin, but more selective than GHRP-6.
The peptide has been extensively characterized in clinical studies and is used as a reference standard for GH secretagogue research. Its diagnostic use in Japan — where a blunted GH response to GHRP-2 injection indicates pituitary dysfunction — demonstrates its well-established and reproducible pharmacology.
Key Research Findings
- •Most potent GH release per dose among classical GHRPs in head-to-head comparison studies
- •Approved in Japan (GHRP Kaken) as a diagnostic tool for GH deficiency
- •Produced synergistic GH release when combined with GHRH analogs (5-10x baseline levels)
- •Less appetite stimulation than GHRP-6 but more cortisol/prolactin elevation than Ipamorelin
- •Demonstrated anti-inflammatory effects through ghrelin receptor activation in sepsis models
- •Improved sleep quality with increased slow-wave sleep in clinical observations
Research Dosage Protocols
GHRP-2 is supplied as lyophilized powder reconstituted with bacteriostatic water for subcutaneous injection.
In clinical diagnostic use (Japan), the standard dose is 100 mcg administered intravenously. Research protocols typically use 100-300 mcg subcutaneously, 1-3 times daily. Due to its short half-life (~20 minutes), multiple daily doses are used in sustained research protocols.
GHRP-2 is frequently combined with CJC-1295 without DAC (Mod GRF 1-29) at matched 100-300 mcg doses for synergistic GH stimulation. Administration timing on an empty stomach is standard.
For research reference only. Not medical advice. Not for human consumption.
Published Research (1 studies)
- [1]
Links go to PubMed (NIH National Library of Medicine). PeptideVerdict is not affiliated with these studies.
Price Comparison (13 products from 9 vendors)
| Vendor | Price | Stock |
|---|---|---|
| Pure Rawz | $35.50 $1.77/mg 20mg vial | In Stock |
| Biotech Peptides | $39.00 $3.90/mg 10mg vial | In Stock |
| Swiss Chems | $19.95 $3.99/mg 5mg vial | In Stock |
| Core Peptides | $20.00 $4.00/mg 5mg vial | In Stock |
| Biotech Peptides | $20.00 $4.00/mg 5mg vial | In Stock |
| Paradigm Peptides | $24.99 $5.00/mg 5mg lyophilized | In Stock |
| Peptide Sciences | $50.00 $5.00/mg 10mg lyophilized | In Stock |
| Particle Peptides | $25.99 $5.20/mg 5mg lyophilized | In Stock |
| Peptide Sciences | $36.00 $7.20/mg 5mg lyophilized | In Stock |
| Peptide Sciences | $36.00 $7.20/mg 5mg lyophilized | In Stock |
| Peptide Sciences | $95.00 $9.50/mg 10mg lyophilized | In Stock |
| Soma Chems | $19.99 vial | In Stock |
| Simple Peptide | $39.00 lyophilized | In Stock |
Frequently Asked Questions
What is GHRP-2?
GHRP-2 is the most potent classical GHRP, approved in Japan for diagnosing GH deficiency. It stimulates strong GH pulses through the ghrelin receptor with moderate off-target effects on cortisol and appetite.
How does GHRP-2 compare to GHRP-6 and Ipamorelin?
GHRP-2 is the most potent for GH release. Ipamorelin is the most selective (fewest side effects). GHRP-6 has the strongest appetite stimulation. GHRP-2 sits in the middle — stronger GH than Ipamorelin, fewer side effects than GHRP-6.
Where can I buy GHRP-2 for research?
GHRP-2 is available from research peptide vendors. Compare pricing in the table above.