Selank — Vendor Pricing & Purity Guide
Research Overview
Selank is a synthetic heptapeptide developed by the Institute of Molecular Genetics of the Russian Academy of Sciences. It is a modified analog of the naturally occurring immunomodulatory peptide tuftsin (a fragment of IgG), with a Pro-Gly-Pro sequence added to improve metabolic stability. Selank is approved in Russia as a prescription anxiolytic and nootropic medication, administered intranasally.
The peptide's mechanism of action is multifaceted. It modulates the expression of brain-derived neurotrophic factor (BDNF) and its receptor TrkB, influences serotonergic and GABAergic systems, and affects the balance of T-helper cell cytokines. This dual activity — both anxiolytic and immunomodulatory — is unique among research peptides. Selank reduces anxiety without the sedation, cognitive impairment, or dependence risk associated with benzodiazepines.
Selank is frequently studied alongside Semax, another Russian-developed peptide with nootropic properties. While Semax primarily enhances cognitive function through ACTH-related pathways, Selank is more focused on anxiety reduction and immune modulation. The two are often researched in combination.
Key Research Findings
- •Demonstrated anxiolytic effects comparable to benzodiazepines without sedation or dependence in clinical studies (Zozulia et al., 2008)
- •Increased BDNF mRNA expression in the hippocampus of rats, suggesting neuroplasticity-promoting effects
- •Modulated the expression of 36 genes related to inflammation and immune response in human blood cells
- •Improved cognitive function (memory and attention) in patients with generalized anxiety disorder in clinical trials
- •Enhanced NK cell activity and normalized T-helper cell balance in immunocompromised models
- •Approved as a prescription medication in Russia (nasal spray) for anxiety and cognitive impairment
Research Dosage Protocols
Selank is typically administered intranasally in both clinical and research settings. The Russian-approved formulation uses a 0.15% nasal spray solution.
In clinical studies, standard dosing was 200-400 mcg per day administered intranasally, divided into 2-3 doses. Research protocols typically run for 14-28 day courses.
For research use, Selank is available as lyophilized powder that can be reconstituted for intranasal administration or subcutaneous injection. Nasal administration is preferred in research as it allows direct access to the CNS via the olfactory pathway, bypassing the blood-brain barrier.
For research reference only. Not medical advice. Not for human consumption.
Published Research (2 studies)
- [1]
- [2]Selank: specific anxiolytic action and effects on brain monoamines— Zozulya et al., 2008PMID: 18577768
Links go to PubMed (NIH National Library of Medicine). PeptideVerdict is not affiliated with these studies.
Price Comparison (28 products from 16 vendors)
| Vendor | Price | Stock |
|---|---|---|
| Particle Peptides | $31.99 $3.20/mg 10mg lyophilized | In Stock |
| Polaris Peptides | $50.00 $3.33/mg 15mg lyophilized | In Stock |
| Peptide Crafters | $35.00 $3.50/mg 10mg lyophilized | In Stock |
| Pure Rawz | $36.72 $3.67/mg 10mg vial | In Stock |
| Limitless Biotech | $117.15 $3.90/mg 30mg lyophilized | Out |
| Peptide Crafters | $45.00 $4.50/mg 10mg blend | In Stock |
| Biotech Peptides | $46.00 $4.60/mg 10mg vial | In Stock |
| Paradigm Peptides | $25.00 $5.00/mg 5mg lyophilized | In Stock |
| Swiss Chems | $25.95 $5.19/mg 5mg vial | In Stock |
| Core Peptides | $52.00 $5.20/mg 10mg vial | In Stock |
| Peptide Sciences | $55.00 $5.50/mg 10mg lyophilized | In Stock |
| Simple Peptide | $55.00 $5.50/mg 10mg lyophilized | In Stock |
| Astro Peptides | $55.00 $5.50/mg 10mg lyophilized | In Stock |
| Skye Peptides | $69.00 $5.52/mg 12.5mg lyophilized | In Stock |
| Biotech Peptides | $65.00 $6.50/mg 10mg vial | In Stock |
| BioLongevity Labs | $134.97 $6.75/mg 20mg vial | In Stock |
| Peptide Sciences | $70.00 $7.00/mg 10mg lyophilized | In Stock |
| Core Peptides | $71.00 $7.10/mg 10mg vial | In Stock |
| Peptide Partners | $234.00 $7.80/mg 30mg | In Stock |
| Skye Peptides | $49.00 $9.80/mg 5mg lyophilized | In Stock |
| Astro Peptides | $352.00 $35.20/mg 10mg lyophilized | In Stock |
| Astro Peptides | $616.00 $61.60/mg 10mg lyophilized | In Stock |
| Limitless Biotech | $56.09 spray | Out |
| Limitless Biotech | $50.99 spray | Out |
| Soma Chems | $34.99 vial | In Stock |
| Soma Chems | $49.99 spray | In Stock |
| Simple Peptide | $60.00 blend | In Stock |
| Simple Peptide | $174.99 lyophilized | In Stock |
Frequently Asked Questions
What is Selank?
Selank is a synthetic heptapeptide developed in Russia as an anxiolytic and nootropic. It is based on the immune peptide tuftsin with added amino acids for stability. It is approved as a prescription nasal spray in Russia.
How does Selank compare to benzodiazepines?
In clinical studies, Selank showed anxiolytic effects comparable to benzodiazepines but without sedation, cognitive impairment, tolerance, or dependence risk. It works through GABA and serotonin modulation rather than direct GABA-A receptor binding.
What is the difference between Selank and Semax?
Both are Russian-developed neuropeptides. Selank is primarily anxiolytic and immunomodulatory (based on tuftsin). Semax is primarily nootropic and neuroprotective (based on ACTH 4-7). They work through different pathways and are often studied in combination.
Where can I buy Selank for research?
Selank is available from research peptide vendors as lyophilized powder or pre-made nasal spray solutions. Compare pricing in the table above.