Kisspeptin-10 — Benefits, Dosage & Where to Buy
Kisspeptin-10 Is Available by Prescription
Kisspeptin-10 is now Category 1, meaning it can be legally compounded by FDA-registered pharmacies with a prescription. Telehealth peptide clinics offer prescribed Kisspeptin-10 with medical oversight. No grey market needed.
Compare Peptide Clinics →Research Overview
Kisspeptin-10 is a truncated form of the 54-amino-acid kisspeptin protein, containing the 10 C-terminal amino acids that are sufficient for full receptor activation. Kisspeptin acts on the GPR54 (KISS1R) receptor in the hypothalamus and is the master regulator of the reproductive hormone cascade - it initiates the GnRH → LH/FSH → testosterone/estrogen axis.
Kisspeptin was discovered when researchers found that mutations in GPR54 caused hypogonadotropic hypogonadism (failure of puberty). A single injection of kisspeptin-10 can acutely stimulate LH and testosterone secretion within 30 minutes. This has made it a major research target for both fertility treatment and understanding the neuroendocrine control of reproduction.
Key Research Findings
- •Master regulator of the HPG axis — a single injection stimulates LH and testosterone release within 30 minutes
- •Mutations in the kisspeptin receptor (GPR54) cause complete failure of puberty in humans
- •Diagnostic potential for differentiating hypothalamic vs pituitary causes of hypogonadism
- •Stimulated LH pulsatility in women with hypothalamic amenorrhea in clinical studies
- •Under investigation as a fertility treatment for both male and female infertility
Research Dosage Protocols
Kisspeptin-10 is supplied as lyophilized powder reconstituted with bacteriostatic water. Clinical research doses range from 1-10 nmol/kg intravenously or subcutaneously. Effects on LH are rapid (within 30 minutes) and dose-dependent.
For research reference only. Not medical advice. Not for human consumption.
Published Research (2 studies)
- [1]
- [2]
Links go to PubMed (NIH National Library of Medicine). PeptideVerdict is not affiliated with these studies.
Price Comparison (11 products from 11 vendors)
| Vendor | Price | Stock |
|---|---|---|
| Paradigm Peptides | $35.00 $3.50/mg 10mg lyophilized | In Stock |
| Simple Peptide | $45.00 $4.50/mg 10mg lyophilized | In Stock |
| Skye Peptides | $49.00 $4.90/mg 10mg lyophilized | In Stock |
| Biotech Peptides | $52.00 $5.20/mg 10mg vial | In Stock |
| Peptide Crafters | $30.00 $6.00/mg 5mg lyophilized | In Stock |
| Core Peptides | $63.00 $6.30/mg 10mg vial | In Stock |
| BioLongevity Labs | $64.97 $6.50/mg 10mg vial | In Stock |
| Pure Rawz | $74.00 $7.40/mg 10mg vial | In Stock |
| Peptide Sciences | $65.00 $13.00/mg 5mg lyophilized | In Stock |
| Swiss Chems | $135.00 $13.50/mg 10mg vial | In Stock |
| Soma Chems | $59.99 vial | In Stock |
Frequently Asked Questions
What is Kisspeptin-10?
Kisspeptin-10 is the active fragment of kisspeptin, the master trigger for reproductive hormone release. It stimulates LH, FSH, and sex hormone production through the GnRH pathway.
What is the difference between Kisspeptin-10 and Kisspeptin-54?
Both activate GPR54 equally. Kisspeptin-10 is the minimal active fragment (10 amino acids vs 54). K-10 is more practical to synthesize and equally potent at the receptor.