Humanin — Benefits, Dosage & Where to Buy
Humanin Is Available by Prescription
Humanin is now Category 1, meaning it can be legally compounded by FDA-registered pharmacies with a prescription. Telehealth peptide clinics offer prescribed Humanin with medical oversight. No grey market needed.
Compare Peptide Clinics →Research Overview
Humanin is a 24-amino-acid mitochondrial-derived peptide (MDP) encoded by the mitochondrial genome. Discovered in 2001, it was the first mitochondrial-derived peptide identified and has demonstrated potent neuroprotective, cytoprotective, and anti-apoptotic effects. Humanin levels decline with age, correlating with increased susceptibility to age-related diseases.
Humanin protects cells from a wide range of toxic insults including amyloid-beta (Alzheimer's), oxidative stress, and serum starvation. It acts through multiple receptors including FPRL1 and a trimeric receptor complex (CNTFR/WSX-1/gp130), activating STAT3 and ERK survival pathways.
Key Research Findings
- •First mitochondrial-derived peptide discovered (2001)
- •Protected neurons against amyloid-beta toxicity in Alzheimer's disease models
- •Declined with age, correlating with increased disease susceptibility
- •Cytoprotective against oxidative stress, serum starvation, and excitotoxicity
- •Circulating levels correlate with longevity in centenarian studies
Research Dosage Protocols
Humanin is supplied as lyophilized powder reconstituted with sterile water. Research doses in animal models range from 1-10 mg/kg via intraperitoneal injection.
For research reference only. Not medical advice. Not for human consumption.
Published Research (2 studies)
- [1]
- [2]
Links go to PubMed (NIH National Library of Medicine). PeptideVerdict is not affiliated with these studies.
Price Comparison (5 products from 5 vendors)
| Vendor | Price | Stock |
|---|---|---|
| Biotech Peptides | $140.00 $14.00/mg 10mg vial | In Stock |
| Core Peptides | $147.00 $14.70/mg 10mg vial | In Stock |
| Peptide Sciences | $155.00 $15.50/mg 10mg lyophilized | In Stock |
| Peptide Partners | $165.00 $16.50/mg 10mg | In Stock |
| Simple Peptide | $99.00 lyophilized | In Stock |
Frequently Asked Questions
What is Humanin?
Humanin is a 24-amino-acid mitochondrial-derived peptide with potent neuroprotective and anti-aging properties. It was the first MDP discovered and protects against amyloid-beta, oxidative stress, and cell death.