Thymagen — Benefits, Dosage & Where to Buy
Thymagen Is Available by Prescription
Thymagen is now Category 1, meaning it can be legally compounded by FDA-registered pharmacies with a prescription. Telehealth peptide clinics offer prescribed Thymagen with medical oversight. No grey market needed.
Compare Peptide Clinics →Research Overview
Thymagen (also known as Thymogen) is a synthetic dipeptide consisting of glutamic acid and tryptophan (Glu-Trp) originally developed in Russia as an immunomodulatory agent. It mimics the biological activity of thymic peptides, promoting T-cell differentiation and maturation, enhancing natural killer cell activity, and modulating cytokine production. Thymagen has been used clinically in Russia and Eastern Europe for immunodeficiency conditions, post-surgical immune recovery, and as an adjunct in cancer treatment. It belongs to the Khavinson school of bioregulatory peptides and is one of the more well-studied short peptide bioregulators, with several clinical trials demonstrating immune system normalization in immunocompromised patients.
Key Research Findings
- •Synthetic dipeptide (Glu-Trp) mimicking thymic peptides
- •Promotes T-cell differentiation and maturation
- •Enhances natural killer cell cytotoxicity
- •Used clinically in Russia for immunodeficiency states
- •Modulates pro-inflammatory and anti-inflammatory cytokine balance
- •One of the most studied Khavinson bioregulator peptides
Research Dosage Protocols
Thymagen (EW dipeptide, Glu-Trp) has been studied in clinical settings in Russia for immunomodulation. Published dosage protocols from clinical practice include:
- **Injectable:** 100 mcg (0.1 mg) intramuscularly or subcutaneously, once daily for 3-10 days. This is the most commonly referenced clinical protocol. - **Intranasal:** Thymogen spray formulations have been used at 25 mcg per nostril, 1-2 times daily for 10 days, primarily for respiratory immune support. - **Repeat courses:** Clinical protocols typically recommend repeating courses 1-3 times per year depending on immune status, with 1-3 month intervals between courses.
Thymagen is a synthetic dipeptide (glutamyl-tryptophan) designed to mimic the active fragment of thymic hormones. It is distinct from thymosin alpha-1 (a 28-amino acid peptide) and thymosin beta-4/TB-500, though all three target immune modulation through different mechanisms. The dipeptide structure gives it high bioavailability and stability compared to larger thymic peptides.
For research reference only. Not medical advice. Not for human consumption.
Published Research (1 studies)
- [1]
Links go to PubMed (NIH National Library of Medicine). PeptideVerdict is not affiliated with these studies.
Price Comparison (7 products from 7 vendors)
| Vendor | Price | Stock |
|---|---|---|
| Peptide Crafters | $70.00 $2.80/mg 25mg lyophilized | Out |
| Swiss Chems | $67.95 $3.40/mg 20mg vial | In Stock |
| Soma Chems | $69.99 $3.50/mg 20mg vial | In Stock |
| Core Peptides | $78.00 $3.90/mg 20mg vial | In Stock |
| Skye Peptides | $79.00 $3.95/mg 20mg lyophilized | In Stock |
| BioLongevity Labs | $79.97 $4.00/mg 20mg vial | In Stock |
| Peptide Sciences | $80.00 $4.00/mg 20mg lyophilized | In Stock |
Frequently Asked Questions
What is Thymagen?
Thymagen (also called Thymogen or EW dipeptide) is a synthetic dipeptide consisting of glutamic acid and tryptophan (Glu-Trp). It was developed in Russia as an immunomodulatory agent designed to mimic the active site of natural thymic hormones. It has been used clinically in Russia for immune support in immunocompromised patients.
Is Thymagen the same as Thymosin Alpha-1?
No. Thymagen is a 2-amino-acid dipeptide (Glu-Trp), while Thymosin Alpha-1 is a 28-amino-acid peptide. Both target immune function but through different mechanisms. Thymosin Alpha-1 has more extensive Western clinical data and FDA orphan drug designation. Thymagen's primary clinical data comes from Russian research programs.
Is Thymagen legal in the US?
Thymagen is currently classified as Category 1 (Rx available), meaning it can be legally compounded by licensed pharmacies with a valid prescription. It is also available from research peptide vendors for research purposes.
What is the difference between Thymagen and TB-500?
Thymagen (Glu-Trp dipeptide) is an immunomodulatory peptide targeting thymic function and immune cell regulation. TB-500 (Thymosin Beta-4 fragment) is a 43-amino-acid peptide primarily researched for tissue repair, wound healing, and anti-inflammatory effects. Despite both being thymus-derived, they have distinct mechanisms and research applications.
How should Thymagen be stored?
Lyophilized (powdered) Thymagen should be stored at -20C for long-term storage or 2-8C (refrigerated) for short-term. Once reconstituted with bacteriostatic water, store refrigerated and use within 28 days.